Ductal carcinoma in situ (DCIS)

Ductal carcinoma in situ (DCIS) in Karachi.

OBJECTIVE To study the frequency of ductal carcinoma in situ (DCIS) in a large pathology series. DCIS is a proliferation of non-invasive, malignant epithelial cells within the ductolobular system of the breast. It is a heterogeneous entity with several morphologic variants that differ in gross appearance, growth pattern, cytologic features, mammography, and malignant potential. METHODS The da...

Diagnosis and management of ductal carcinoma in situ (DCIS).

OBJECTIVES Systematic synthesis of the published evidence about incidence, risk factors, and management options for women with ductal carcinoma in situ (DCIS) of the breast. DATA SOURCES Original epidemiologic studies were sought from several databases to identity articles published in English between 1970 and January 31, 2009. REVIEW METHODS Incidence of DCIS in the general population and ...

The management of lobular carcinoma in situ (LCIS). Is LCIS the same as ductal carcinoma in situ (DCIS)?

Lobular carcinoma in situ was first described over 60 years ago. Despite the long history, it continues to pose significant difficulties in screening, diagnosis, management and treatment. This is partly due its multi-focal and bilateral presentation, an incomplete understanding of its biology and natural history and perpetuation of misconceptions gathered over the last decades. In this review, ...

Ductal carcinoma in situ (DCIS) of the breast: perspectives on biology and controversies in current management.

The incidence of ductal carcinoma in situ (DCIS) has increased because of increasing use of sensitive imaging modalities. MRI is commonly used for the detection of breast cancer but has not yet been validated in randomized trials. There have not been randomized trials addressing optimal margins of excision or axillary sampling. Whole breast radiation after lumpectomy decreases the risk of recur...

Detection of pure ductal carcinoma in situ (DCIS) at diffusion-weighted imaging (DWI)